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Chantix or Champix - nosmoke@aipharma.com

This page is provided for professional use only. For International (licensed) buyers of pharmaceuticals (such as Hospitals, Pharmacies and other wholesalers).

Varenicline is sold as 0.5 mg and 1 mg tablets. Titrating the dose from 0.5 mg every day for 3 days to 0.5 mg twice daily for 4 days to 1 mg twice daily is recommended. The standard maintenance dose is 1 mg twice daily, with variations as permitted by the FDA. The FDA has approved its use for twelve weeks. If smoking cessation has been achieved it may be continued for another twelve weeks.

INDICATIONS:
CHAMPIX is indicated as an aid to smoking cessation treatment.

More comprehensive information is available at:

www.chantix.com

Articles found on the internet concerning "Chantix" and "Champix"

(CNW) UK Body Recommends Pfizer's Champix (varenicline) for Smokers

Smokers in the UK Should Now Have Access to Champix

NEW YORK, May 30 /CNW/ - Pfizer Inc announced today that the National Institute for Health and Clinical Excellence (NICE) in the United Kingdom has recommended Champix (varenicline) for use on the National Health Service for adult smokers who have expressed a desire to quit. This gives smokers across England, Wales and Northern Ireland access to another important treatment option to help them quit smoking.

In its Final Appraisal Determination, NICE concluded that varenicline was "superior to NRT (nicotine replacement therapy) and bupropion in achieving continuous abstinence" and that its use in smoking cessation was "likely to be a cost-effective use of National Health Service resources."

"This guidance means that smokers who are serious about stopping have another choice from a good range of clinically proven treatments, said Professor Robert West, Professor of Health Psychology at University College London. "Smokers who combine treatments with the right support - for instance from smoking cessation services - could significantly increase their odds of successfully quitting for life."

Champix is the first new prescription aid to smoking cessation treatment in nearly a decade. Pfizer discovered and developed Champix specifically as an aid to smoking cessation through its unique mechanism of action targeting the specific receptor to which nicotine binds. Champix is believed to work by reducing the severity of the smoker's urge to smoke.

"This guidance in the U.K. recognizes the efficacy and cost-effectiveness of Champix, and encourages physicians and smokers to consider this treatment as a new treatment option to help smokers quit smoking," said Jack Watters, MD, Pfizer's Vice President of International Medical Affairs. "The implications of this ruling are particularly timely as they come just before World No Tobacco Day, when organizations and governments around the world will work to implement smoke-free policies, which may further encourage smokers to make a quit attempt."

Smoking, the leading cause of preventable death worldwide, is responsible for five million deaths worldwide each year. By 2010, the World Health Organization estimates the annual global cost of tobacco-related illness to be approximately US$500 billion.

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Champix: Just Another Name For Chantix

Are you aware of the fact that Champix is nothing but another name for the FDA approved quit smoking drug Chantix? Well, only a certain section of people around the world are acquainted with this fact and the other half who are really ignorant of the relationship between Chantix and Champix fall into utter perplexity when they get hold of Champix while looking for the quit smoking medicine Chantix. So, to inform you the real truth on Chantix as well as Champix, a couple of pointers are mentioned below:

Varenicline Tartrate is the generic name of Chantix as well as Champix.
Intially, Pfizer selected Champix as a brand name for Varenicline Tartrate but the Food and Drugs Administration, USA(FDA) rejected it citing that the name Champix is “overly fanciful and overstates the efficacy of the product” from the promotional point of view. As a consequence Pfizer changed the name to Chantix, obtained FDA approval for the drug on May 11,2006 and launched Chantix as an anti-smoking medicine in US under the same name. But the brand name Champix for Varenicline Tartrate was accepted by the European Commission a few months after the launching of Chantix in the pharmaceutical market and on September 29, 2006, the drug was relaunched as Champix in the European countries. On 14 th January, 2007 Champix was made available for sale as a prescription-based quit smoking medicine on the Scotland National Health Service(NHS).

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Tobacco smoking is the leading cause of premature death in developed countries. Approximately half of all long-term smokers die prematurely due to smoking-related health problems, and continuing smokers have a reduced lifespan by an average of ten years. In contrast, individuals who quit smoking by age 50 reduce their risk of dying in the following 15 years by about one-half compared with those who continue to smoke.

Pfizer's Champix (Varenicline) is a new agent for smoking cessation with a different mechanism of action than currently available medications.

What is CHAMPIX?
Varenicline is indicated for smoking cessation in persons eighteen years of age and older.

How does CHAMPIX work?
It is a partial agonist that binds selectively and with greater affinity than nicotine to alpha 4 beta 2 nicotinic acetylcholine receptors. It produces an effect that relieves symptoms of withdrawal and craving, at the same time, it prevents nicotine from binding to the receptor, thus blocking the rewarding and reinforcing effects of smoking.

How effective CHAMPIX is?

Studies demonstrate that varenicline was superior to both placebo and bupropion in short-term efficacy. Consistent benefit over placebo was also shown in the long term (at week 52), whereas results were inconsistent with respect to long-term efficacy against bupropion.

What are the adverse effects of CHAMPIX?

Varenicline was generally associated with mild to moderate adverse events in clinical trials. Nausea was the most frequently reported adverse reaction . It appears to be dose-dependent and usually decreases with continued use. One study found a lower incidence of nausea when the drug was titrated to target doses over a few days.

Other common adverse reactions reported with varenicline were vomiting, constipation, flatulence, taste perversion, abnormal dreams, and sleep disturbance.

Unlike bupropion SR and most nicotine products, varenicline does not decrease weight gain associated with smoking cessation.

Are there any drug interactions with CHAMPIX?

No known clinically meaningful drug interactions have been identified based on drug interaction studies between varenicline and digoxin, warfarin, bupropion, cimetidine, or metformin. Concomitant therapy with transdermal nicotine does not appear to affect nicotine pharmacokinectics, however, the incidence of gastrointestinal (nausea, vomiting, dyspepsia) and neurologic (headache, dizziness,fatigue) symptoms was higher with the combination than with nicotine alone.

What is the recommended dosing for CHAMPIX?

It is recommended that varenicline be started one week prior to a patient's target quit-smoking date, with the dose titrated to 1 mg twice daily as follows:

Day 1-3: 0.5 mg once daily
Day 4-7: 0.5 mg twice daily
Day 8 through the end of week 12: 1.0 mg twice daily

Varenicline should be taken after a meal, with a full glass of water.

The medication, varenicline, with tradename ChantixTM (varenicline) in the United States, received U.S. Food and Drug Administration approval as an aid to smoking cessation in May 2006.

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Smoking cessation
From Wikipedia, the free encyclopedia
Jump to: navigation, search
For My Name is Earl episode, see Quit Smoking (My Name Is Earl).

Smoking cessation (commonly known as quitting, or kicking the habit) is the effort to stop smoking tobacco products. Nicotine is a psychologically and physically addictive substance, and quitting smoking is commonly considered to be difficult. Psychological and pharmacological aids are available to help people quit smoking, although success rates are relatively low. As part of the wider tobacco control movement, there have been numerous advertising campaigns, smoking restriction policies, tobacco taxes, and other strategies to encourage people to quit smoking. Tobacco use is a major cause of death worldwide, according to the World Health Organization.

Contents:
1 Outline
2 Women and Smoking Cessation
3 Statistics
4 Methods
4.1 Screening
4.2 Modalities
4.3 Alternative techniques
5 See also
6 References
7 Notes
8 External Links

Outline:
Smoking cessation services, which offer group or individual therapy can help people who want to quit. Some smoking cessation programs employ a combination of coaching, motivational interviewing, cognitive behavioral therapy, and pharmacological counseling. Programmes in the UK are run by the NHS, and use a clear and clinically tested protocol. However evaluation of the NHS programme has shown disappointing outcomes.

Trials have shown that an effective method for quitting smoking is cognitive behaviour therapy. For example, the QUIT FOR LIFE Programme (David Marks, 1993, 2005) has produced quit rates that are 5-6 times higher than quitting by willpower alone (Marks & Sykes, 2002).

One effective way to assist smokers who want to quit is through a telephone quitline which is easily available to all. Professionally run quitlines may help less addicted smokers but those more severely addicted to cigarettes (ie anyone who smokes within half an hour of waking) should seek out their local smoking cessation services, where they exist, or assistance from a knowledgeable health professional, where they do not. Evidence shows that best results are achieved when support and medication are used simultaneously. Quitting with a group of other people who want to quit is a proven method of getting support, available through many organizations.

A serious commitment to arresting a dependency upon smoking nicotine is essential. Medication, such as a nicotine replacement therapy product or Wellbutrin (aka Zyban) have been clinically proven to double a quitter's chances of stopping successfully versus placebo.

However, critics have drawn attention recently to the risks associated with the administration of nicotine, a poison, to pregnant women and adolescents (Ginzel et. al., 2007).

Although a significant proportion are successful, many people fail several times. Many smokers find it difficult to quit, even in the face of serious smoking-related disease in themselves or close family members or friends.

Studies have concluded that those who do successfully quit smoking often gain weight. "Weight gain is not likely to negate the health benefits of smoking cessation, but its cosmetic effects may interfere with attempts to quit." (Williamson, Madans et al, 1991) Therefore, drug companies researching smoking-cessation medication often measure the weight of the participants in the study.

Women and Smoking Cessation:
Major depression may influence smoking cessation in women. Quitting smoking is especially difficult during certain phases of the reproductive cycle, phases that have also been associated with greater levels of dysphoria, and subgroups of women who have a high risk of continuing to smoke also have a high risk of developing depression. Since many women who are depressed may be less likely to seek formal cessation treatment, practitioners have a unique opportunity to persuade their patients to quit.

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How Supportive Are You?
By Sandy Tonsing

Do you want your loved ones to quit smoking, your dad, mom, girl friend, boy friend, friends and relatives to kick the butt and stay smoke free? How helpful are you in helping them change their habit? Are you supportive enough or are you the kind who knows only how to complain and ridicule the smokers? If so it’s a high time you lend a helping hand and change your “holier than thou” attitude. Time and again we keep on pointing our fingers at smokers and even ridicule them when they say they are about to quit. Non-smokers always have this attitude that they are clean and that they totally hate smokers and consider them to be some kind of disease spreaders. Do you think that a smoker doesn’t want to quit smoking? I doubt there would be any smoker who doesn’t want to quit, they all wanna quit, and it’s just that they are not strong enough to try on their own. That’s the reason why they need your love and support more than anything else.

Since the addiction of nicotine is much harder to kick than heroin, cocaine and alcohol, smokers often fail in their attempt to quit smoking. Nicotine works in the brain by activating dopamine which is a neurotransmitter and is responsible for the normal functioning of the central nervous system. Therefore when people begin to depend on nicotine, it controls them; it affects their behavior and moods. The addictive nature of Nicotine is that it is a stimulant and also a depressant.

Therefore, if a smoker finds it difficult to quit, do not laugh at him/her instead understand their situation and give a shoulder to lean on. You don’t need to do much just believe in them, become their activity partner, give them your trust, motivate and cheer them up when they are on the brink of giving up. You can help your loved ones to quit by being supportive and by lending an ear and listening to whatever they have to share. The most important thing is accept them as they are, encourage them but never force them to quit smoking.

You may also give presents like nicotine replacement products and medicines to make their quitting easier. If you go for the medicines, chantix by Pfizer which is also known as champix in European countries is the best choice. It has been used by many people and is giving quite remarkable results. Due to its effectiveness thousands of smokers are able to quit smoking.

Chantix is not a nicotine replacement nor is addictive, it is a prescription medicine approved by FDA for the treatment of anti-smoking in adults. It works in the brain by undoing whatever nicotine had done. It also diminishes the taste of cigarette i.e. even if a smoker smokes after taking chantix he doesn’t feel the same taste or pleasure he used to feel before. Further, it remarkably cuts down the cravings or the urge to have cigarette.

So if you want your loved ones to quit smoking change your attitude and buy chantix for them. You will remember this great act of yours with fond memories in days to come. Isn’t it overwhelming to know that because of you somebody could quit their bad habit? Your loved ones will be thankful to you through out their life for saving them from preventive death.

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Chantix and Champix

This year varenicline (Chantix and Champix) is the new kid on the block. Pfizer boasts that it aided 1 in 5 clinical trial users in quitting for a year. But aside from Chantix/Champix use, a number of study design factors may have heavily influenced outcome. More alarming, there's mounting user concerns that Pfizer has failed to adequately warn smokers about adverse events, including "frequent" risk of significant muscle and joint pain (what Pfizer lists as "arthralgia, back pain, muscle cramp, musculoskeletal pain, myalgia" - see page 14), without telling users how frequently, or that symptoms may persist long after varenicline use has ended.

http://forums.wrongdiagnosis.com/showthread.php?t=2301

Link to Pfizer's complete list of
Chantix / Champix Adverse Events

http://www.pfizer.com/pfizer/download/uspi_chantix.pdf

But if the Chantix / Champix user makes it past the side-effects, they truly will experience up to 60% of the dopamine output that nicotine would have generated if sitting on the exact same acetylcholine receptors. The trick with Chantix / Champix isn't in feeling comfortable while using it but adjusting to living without it, as more than half of clinical trial users who quit smoking for 3 months while using varenicline relapsed within a year.

If you have a friend or loved one using Chantix or Champix there's absolutely no reason, whether they continue using it or not, that they cannot go the distance and succeed, so long as zero nicotine finds its way back into their bloodstream. Key is relapse prevention. You may want to send them the link to downloading Joel's free PDF book "Never Take Another Puff" which can be downloaded at:

http://whyquit.com/joel/

Reporting Adverse
Chantix / Champix Events

If you know someone using Chantix or Champix who experiences significant side effects encourage them to ...

immediately call their physician

Also, encourage them to report the adverse reaction to their national health officials. Here's a few links:

U.S. Food & Drug Administration - http://www.fda.gov/medwatch/

U.K. Medicines and Healthcare Products Regulatory Agency
http://www.mhra.gov.uk/home/idcplg?IdcService=SS_GET_PAGE&nodeId=755

Australian Therapeutic Goods Administration
http://www.tga.gov.au/adr/bluecard.htm

Canadian Adverse Drug Reaction Monitoring Program
http://www.hc-sc.gc.ca/dhp-mps/medeff/report-declaration/guide/ar-ei_guide-ldir_e.html

Keywords for this page: Order Chantix - Buy Chantix - Chantix Supplier - Chantix Supply - Chantix Wholesaler - Order Champix - Buy Champix - Champix Supplier - Champix Supply - Champix Wholesaler

07-01-2007, 13:51 #1
SMK
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Adverts | Blog | Friends Champix/Chantix - anyone got any information?

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I've been reading about a new "stop smoking" drug called Champix (Chantix in USA). It was just released a few weeks ago. I went to my doctor but he didn't know enough about it and wants to research it first before prescribing it.

I can't find much information about it on the internet other than information put out by the manufacturers.

Has anybody heard about it or tried it?

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07-01-2007, 15:09 #2
dumbyearbook
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Adverts | Blog | Friends Hey,

Dunno if its the same one but I heard of a medication that you do a 3 week course of it (€100 a go) a friend of a friend is taking it, I'll ask her how she gets on and post the outcome

- was thinking of getting it myself too but ill let Alan Carr get to work first!

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08-01-2007, 16:41 #3
gramlab
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Adverts | Blog | Friends Not much here but..........

A Different Way to Help Quitters Quit

Good News for Smokers
There’s good news for smokers this week with the launch of Champix™ in Ireland. Champix, is the first new prescription aid to smoking cessation treatment approved by the EMEA and U.S. Food and Drug Administration in nearly a decade, and it is now available to Irish patients. Those who are prescribed Champix will be offered the opportunity to enroll in a behavioural modification programme called Life RewardsTM Support Plan at no additional cost. The plan was developed by Pfizer with input from smoking cessation experts.

“By launching Champix in Ireland to help people quit smoking, we hope to take a positive step toward improving the health of smokers, their families and friends, and society in general,” says Jay Cusack, Champix Brand Manager. “Quitting smoking is challenging physiologically and psychologically. Very often, smokers are very much on their own during the difficult quitting process. To help people break free from the powerful grip of smoking, we are offering Champix with a personalised behaviour modification program called Life RewardsTM Support Plan. It is our hope that this will help smokers achieve their goal of living smoke-free.”

Decline in Smoking has been Reversed
According to the Office of Tobacco Control the overall prevalence of cigarette smoking in Ireland is approximately 24%. There was a decline in smoking prevalence after the smoke free legislation in March 2004, however this decline has now been reversed. In particular there is a rise in smoking prevalence among young women. 25% of the female population smoke. There is also a reversal in the decline in smoking among 15-18 year olds and 19-35 year olds generally. It is estimated that 18% of 15-18 year olds smoke and 33% of 19-35 year olds. Half of all smokers will die from tobacco related disease and of these 50% will die prematurely. In Ireland 7,000 people die every year from tobacco related diseases. Annually 1,500 people die from lung cancer. Smoking causes 30% of all cancers, including 90% of lung cancers.

Four out of every 5 smokers wish they had never started. Champix offers an important advance in smoking cessation. It is the first in a new class of medicines called selective nicotinic acetylcholine receptor partial agonists and it works by binding to the nicotinic receptors and providing relief from the craving and withdrawal symptoms while also reducing satisfaction and the rewarding effects of smoking.

A Death Every Eight Seconds
Smoking is the world’s leading preventable cause of premature death. While many smokers would like to quit to prevent further damage to their health, the World Health Organisation (WHO) estimates that less than 5% of smokers trying to quit unaided remain abstinent at 1 year. It is believed that most smokers continue to smoke not out of choice, but because they are addicted to nicotine. Addiction to nicotine is a chronic, relapsing medical condition. Worldwide, approximately 1.3 billion people currently smoke cigarettes. Approximately five million people die of smoking-related diseases each year worldwide and the WHO estimates that if current smoking patterns continue, the number of people dying of smoking-related diseases globally will double by 2020 to 10 million a year. According to the WHO, every eight seconds a person dies of a smoking-related disease (and almost as quickly someone else takes up smoking for the first time).

Further information on smoking and quitting can be found on the following websites: ASH Ireland: www.ash.ie, Irish Heart Foundation: www.irishheart.ie , Irish Cancer Society: www.cancer.ie, Office of Tobacco Control: www.otc.ie
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30-01-2007, 19:17 #4
the Guru
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I'm starting it again tomorrow, I did start it a few weeks ago but I didn't want to mix with with other meds I was taking. 2 of the lads in the office are taking it and they where really heavy smokers and they have stopped.

It does work
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01-02-2007, 21:05 #5
SMK
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Adverts | Blog | Friends I got the Champix and today was day 14 of the tablets. I stopped smoking yesterday so I've almost completed Day 2 as a non-smoker!! Craving are definitly a lot easier to handle and I think I might actually succeed this time in staying off the cigs! Very annoying though when I "forget" I'm not smoking and reach for cigarettes that aren't there!! But hopefully that will pass soon.

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29-03-2007, 16:00 #6
dragona
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Adverts | Blog | Friends Can someone give me an idea of how much Champix costs? I used Zyban a good few years ago and stopped for nearly a year -something set me off again, but would like to try this new one, if the price is not prohibitive.

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30-03-2007, 09:29 #7
gramlab
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Adverts | Blog | Friends 2 week starter pack is @65 euro. 125 monthly after that if you carry on.

MAKE SURE YOU GET A DPS CARD and you only pay max of 85 euro a month for anything prescribed i.e 1st month almost free
I've benn off them now for 6 weeks which is about 6 weeks better than any other attempt (23 years a smoker). Have tried Alan Carr clinic twice, read the book, patches, gum etc and none worked for me. Don't know if its the champix or just the fact that I know if this doesn't work I haven't really got any options left thats keeping me going but finally know what its like to be off them a while and it feels good
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Last edited by gramlab : 30-03-2007 at 09:34.

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01-04-2007, 13:22 #8
knighted
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Adverts | Blog | Friends can any doctor prescribe this or just selected ones ?

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02-04-2007, 09:19 #9
gramlab
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Adverts | Blog | Friends Any doctor can prescribe it. It was not even officially launced when I started it and you will still find it hard to find a chemist that stocks it - they can order it in in a day or two.

Good luck if you try it.
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04-04-2007, 14:11 #10
Nan
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Adverts | Blog | Friends Champix worked for me...

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Hi All,

Stopped smoking Jan. 19th. while taking Champix. Felt great emotionally - almost as if tranquillized. Physically, I didn't have any cravings, but I was bloated for about two weeks: very unpleasant. I slept like a baby, had wonderfully funny and quirky dreams and didn't gain weight.

I am still smoke and nicotine free and have discontinued Champix. I am convinced that Champix helped me get started and that without it, I would not have got this far. But...

...several side effects became too unpleasant. Serious one: I started coughing up small amounts of blood, so after discussing it with the doc, I simply halved the dose and everything was fine. I then started becoming angry and aggressive and halved the dose again. Through all this, I have had only a few terrible moments where I have felt so tempted that I might have smoked had I a cigarette in hand - luckily I didn't.

A week or so ago, I started shouting at a dog trainer (really shouting), and I knew it was time to completely discontinue the tablets. I did it slowly and have been fine. I am careful about what I eat and do not set myself up for failure. I haven't smoked since Jan. 19th. and I feel hopeful that I can stay the course, which has been made a lot easier by starting with Champix.

Still, I would never take it for six, let alone nine months....

Nan

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02-05-2007, 20:28 #11
loumac
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Adverts | Blog | Friends Champix

--------------------------------------------------------------------------------

My brother is taking it & I'm going to start this week.I was always wary of Zyban & this seems way better. My brother is late 40's, has been on Champix for a month & said the cravings stopped after a matter of days. He really doesn't want a smoke! There are no side effects that he notes other than mild heart burn (which may be unrelated) Beat's cancer!

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31-05-2007, 15:03 #12
gafarrell
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--------------------------------------------------------------------------------

Well,
This Champix drug is now been given out free by the NHS in the UK from today i believe. I am thinking of giving something a go real soon and this looks like a good option. If anybody knows where to get it in Cork please let me know (Or do it have to be prescribed by a doctor?)

Cheers

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31-05-2007, 17:46 #13
SMK
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Adverts | Blog | Friends You have to get a prescription from your doctor for it. I've been using Champix and I'm off the cigarettes over six weeks now. I didn't follow the instructions exactly! I started it in January and was stopping and starting smoking until 15 April when I finally stopped for good! Although soon after starting the drug I had cut down to about 10 a day. I still get cravings but they are easier to manage and I haven't even come close to lighting up since I quit for good. And I started a diet the same day and have lost 9lb so far!!

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03-06-2007, 01:23 #14
JohnRPolito
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Adverts | Blog | Friends Understandably, there's lots of excitement each time a new quitting product arrives. But long-term smokers have lived broken marketing promises for at least 25 years. Will Champix be different?

Pfizer's press release boasts that 1 in 5 Champix users remained quit for an entire year but, frankly, the design of Pfizer's 5 studies was utterly horrible. They make it impossible to tell how much of the one-year rate to attribute to Champix and how much to other factors such as: (1) excluding hard to treat populations, (2) up to 25 provider support and/or counseling contacts, contacts having their own efficacy (possibly a record), and (3) allowing Champix users to use NRT products following 3 months of Champix use, yet counting them as successful Champix quitters. But then again, out in real world use ... who knows how it'll fare.

For those interested here's two critical study design reviews:

http://whyquit.com/pr/082506.html

http://whyquit.com/pr/121606.html

The problem for those surviving adverse events and side-effects isn't in being comfortable while on Champix (which really isn't too hard to do as it puts out up to 60% of the dopamine that nicotine would have if sitting on the exact same nicotinic receptor that varenicline now occupies 24 hrs a day) but in adjusting to coming off of it and successfully transiting the period of time which the brain needs to down-regulate receptor counts. Keep in mind that more than half who successfully completed three months of use relapsed to smoking within a year.

Is Champix more effective than the nicotine gum, patch or lozenge? We all certainly hope so but I'm not holding my breath. As shared in the top link, a number of early nicotine gum studies, that also included heavy counseling and/or support elements, generated one-year quitting rates higher than Champix. But we've since learned that when nicotine gum is used as a stand-alone over-the-counter product, its six month (not 1 yr) quitting rate is a dismal 7%, with a substantial percentage of that 7% (up to 6.7%) still hooked on the cure.

As for adverse events, this is not Zyban or Wellbutrin (bupropion), where we were each told and knowingly accepted a 1 in 1,000 risk of having a seizure. Significant Champix side effects are clobbering so many users that it's nearly impossible not to hear their voices. Take a look at this link:

http://forums.wrongdiagnosis.com/showthread.php?t=2301

If true, imagine significant muscle and joint pain for days or weeks after Champix use has ended. I'm working with a couple of dozen Champix users in helping prepare them to stay free once they come off of it. I've encouraged all of them to read either Joel Spitzer's free book "Never Take Another Puff" available at http://whyquit.com/joel/ or Allen Carr's free book "Scandal" available at http://www.ciggyfree.com/SCANDAL.pdf

With or without Champix, yes you can! In the end there's just one rule determining the outcome for all ... no nicotine today, Never Take Another Puff, Dip or Chew!

John R. Polito
Nicotine Cessation Educator

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04-06-2007, 09:17 #15
Nan
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Adverts | Blog | Friends Quote:
Originally Posted by JohnRPolito
[...]

As for adverse events, this is not Zyban or Wellbutrin (bupropion), where we were each told and knowingly accepted a 1 in 1,000 risk of having a seizure. Significant Champix side effects are clobbering so many users that it's nearly impossible not to hear their voices....

Hi John,

Thanks for the great links.

Certainly, it was very difficult to find the low down on Champix as it's called here in Denmark. I work as a translator and have good Internet search skills without which I would not have found the information about the medical trials. Even so, I had to lie to get the information: "Yes, I am a doctor." or some such sentence that allowed me to get the information. Loads of hard-to-understand stastistics and jargon not known to the average joe or josephine. I mostly agree with your assessment.

I am still smoke, pill and nicotine free. Almost five months --- soon.

Whether due to Champix or cessation, my body continues to behave in unaccustomed ways. Would I still have taken Champix? Yes. Literally armed with information, I could not have foreseen some of the side-effects and would probably, had I known, have stayed on the initial half dose.

The real medical trial is when the product hits the market.

Again, thanks for the links.

Nan

Has anyone heard of Pfizer's Chantix
COMMENTS
Matt New York
AOL Reply »
|Flag |#21 Jan 25, 2007
I am going into 9th week of Chantix. Have not smoked for 8 weeks. Very satisfied so far, however does anyone know anything about withdrawal from Chantix?
It concerns me Phizer has a hotline entitled "Chantix cravings."
Ramona Texas
Driscoll, TX Reply »
|Flag |#22 Jan 26, 2007
Matt New York wrote:
I am going into 9th week of Chantix. Have not smoked for 8 weeks. Very satisfied so far, however does anyone know anything about withdrawal from Chantix?
It concerns me Phizer has a hotline entitled "Chantix cravings."
Matt there is a website called thecancerblog.com and they talk about tapering off of chantix. It may be helpful. This is day 3 for me and I am very excited.
Lynne Michigan
Ann Arbor, MI Reply »
|Flag |#23 Jan 29, 2007
This is my fourth day of being a non smoker, thanks to Chantix. I have smoked approx. 2 packs a day, for 30+ years, and I NEVER thought I would be able to quit. For the first time I truly think I can do it. This time with Chantix it is actually very easy. NO cravings! I have not had any side effects, no nausea, nothing. I LOVE IT!!!!!!!!!!
Jennifer
Lexington, KY Reply »
|Flag |#24 Jan 30, 2007
I started chantix 1/2/07 and smoked my last cigarette 1/12/07. I smoked for 18 years 1pack a day. I was very tired in the beginning but it has gotten better and i am getting my energy back. I seriously think I was so tired because I really was not sure what to do with myself since I didnt have a cigarette to "motivate" or "reward" myself anymore when doing daily tasks. It was just easier for me to lay around or take a nap. I told myself that it was ok to be lazy for awhile, whatever it takes to conquer this nasty habit. I am now alot more adjusted to not smoking and realize that I can do things without having to smoke before or after I do them. Good Luck
Brian
Marion, VA Reply »
|Flag |#25 Jan 31, 2007
Connie wrote:
I have heard a lot of other people complain of being so tired. Nicotine is a stimulant, so without it you lose the stimulation. I wish Chantix would have addressed that issue also. I think it also lowers your immune system. I am taking No-Doze during the day just to stay awake. Anybody else having the same problems?
Yes, very tired and vivid dreams, along with general melancholy. I started taking Chantix on January 8 to help nip a 30-year smokeless tobacco addiction. It seems to work and work quite well, though the next item on the agenda is getting off the Chantix. D'oh! Is anyone aware of discontinuation syndrome associated with Chantix? Good luck to all and fight the good fight.
Connie
Fremont, NE Reply »
|Flag |#26 Jan 31, 2007
Ramona Texas wrote:
<quoted text>
Matt there is a website called thecancerblog.com and they talk about tapering off of chantix. It may be helpful. This is day 3 for me and I am very excited.
I went to thecancerblog.com but couldn't find anything about tapering off of Chantix. Has anyone else seen it? That would be really interesting to read.
Connie
Fremont, NE Reply »
|Flag |#27 Jan 31, 2007
I went to thecancerblog.com but couldn't find anything about tapering off of Chantix. Has anyone else seen it? That would be really interesting to read.
Brian
Scottsdale, AZ Reply »
|Flag |#28 Feb 1, 2007
I am on week 3 and day 1. I am still smoking. I see only a minor change in how I feel to smoking. The cigarettes aren't as good as they were in the past. But that is it. Also, I feel like I have quite cold turkey again with no assistance from medicines. I am very irritable and I am still smoking. I quit Chantrix for one weekend and I felt my normal self again. Also while on it, my dreams have been chaotic. I remember everyone of them like I was there. And I also feel sick too.
Zebbie Indiana
Logansport, IN Reply »
|Flag |#29 Feb 1, 2007
I have order Chantix through my prescripton plan and, thankfully they pay all but $10. I went ahead and got it for $5 through the mail, just have to wait 14 days for it. Here is my big concern. The side effects. I hate taking medician and if I hear it has a bad side effect I wont even try it. Like I herd this one may cause difficulty in breathing granted it is not one of the main sie effects. This is my concern. I have been a smoker for 29 years, started at the ripe old age of 13, to know now then!!! My husband is a non smoker and wants me to quit. I smoke about a 1/2 pack a day. I don't smoke infront of him out of respect. So the only thing I am hearing is tiredness and some nausea. I hope that is it for me. And does the tiredness go away?
Dave Sweet
Salt Lake City, UT Reply »
|Flag |#30 Feb 2, 2007
Purchased mine three days ago and the cost was $115.00 for the "Starter Kit". This covers the initial 12 weeks. Maybe all that's needed.
ajtih wrote:
Can any one tell how much this costs, I mean the whole program. Also you if you think you got over the habit can you quit the program too..???
Marks girl
Geneva, OH Reply »
|Flag |#31 Feb 4, 2007
I have been on Chantix and have not had a cigarette since 1/10/07. I can't believe how easy it was. I had quit on the patch for 6.5 years and it was pure hell. This is so easy. I do get nauseated in the morning but it isn't anything that can't be handled. I am concerned about what happens when I go off the Chantix. Has anybody weaned off the chantix yet?
Anna Woods
Chute, UK Reply »
|Flag |#32 Feb 5, 2007
I have been using Chantix(called Champix in UK) for 5 days now to get off nicotine gum addiction. On he first day the gum didn't seem to work anymore so I stopped it straight away. Cravings are happening but they are mild. Lets hope it's easy to get off Chantix as the gum never had the same pleasure as smoking and being addicted to Chantix would be even less fun. In the UK Champix is available on the NHS and costs only £6.70.
Tom
Dearborn, MI Reply »
|Flag |#33 Feb 5, 2007
Marks girl wrote:
I have been on Chantix and have not had a cigarette since 1/10/07. I can't believe how easy it was. I had quit on the patch for 6.5 years and it was pure hell. This is so easy. I do get nauseated in the morning but it isn't anything that can't be handled. I am concerned about what happens when I go off the Chantix. Has anybody weaned off the chantix yet?

I stopped smoking 12/25/06 and took my last Chantix on 1/14/07. It wasn't a big deal for me but I'm sure everyone is different. I'm still not smoking and I'm at the point where I really don't think about it(smoking) much anymore.I feel I'm well on my way and confident I won't smoke. Chantix is awesome. I'm extremely happy I started takig it and think its really up to the individual whether or not it works.
kelly
Evansville, IN Reply »
|Flag |#34 Feb 5, 2007
dringing ALOT of fluid, drinking fruit juice, or munching on carrots will help alot with the fatigue associated with quiting smoking. it will safely keep your blood glucose up, and give you a little extra energy to get through the first phase of quiting. it takes ONLY 3-4 days to FULLY release the nicotine from your system...and about a week or two to get over the fatigue
Connie wrote:
have been on Chantix for 3 weeks, and have been successful in not smoking. I was a 2-3 pack a day smoker. The one thing they don't address though, is the nicotine withdrawal. Nicotine is a stimulant. Instead of weaning you off, it's just cold turkey. I have been sleeping more and more also, and tired all the time. I think the idea of Chantix is good, but they should have coupled it with something for the nicotine withdrawal. Would like to hear if anyone else had this happen with Chantix?
Anna Woods
Saint Mary Cray, UK Reply »
|Flag |#35 Feb 7, 2007
Does anyone know if you get wathdrawal symptoms when you come off Chantix or do you have to wean off slowly to avoid craving cigarettes? It would be hard to go through withdrawal yet again.
Cathy Ottawa Canada
Ottawa, Canada Reply »
|Flag |#36 Feb 7, 2007
I'm thinking of trying Chantix to stop smoking. I did try Zyban but ended up having a major panic attack as a side effect (thought I was having a heart attack!). Has anyone experienced any increased anxiety from taking Chantix?
Diane
Tucson, AZ Reply »
|Flag |#37 Feb 8, 2007
I am day 10 of Chantix and on my third day of not smoking. I was a 20-22 a smoker for approximately 26 years (started at 16 and I am now 38). On effectiveness, I think Chantix is a miracle. With a biochem background, I do understand how it works, and do understand that it dulls the craving because it stimulates nicotine receptors all the while, but even knowing this I cannot help think this is far and away the most effective quit aid I have ever tried.

On day 3 of not smoking, I firmly think of myself now as a non-smoker. And I do want to point out I think you do have to *want* to quit. Cravings still come and go, but as early as day one of my quit the majority of them feel as if they are wrapped in cotton -- vague, slightly nagging, all overcome with a fairly easy "no, I don't smoke" reminder to myself, and that's it. I have experienced *none* of that I'm-going-to-poke-someone's-ey e-out irritable of cold turkey/NRT quits I have tried and I have had zero side effects so far from the Chantix.

As for the person who asked about anxiety: Quite frankly, Chantix has made feel extremely mellow and serene, feels almost as if I've taken a valium or a percocet or something. This is, no doubt, from the constant low grade nictotinic receptor stimulation. This raises some concern on my part about withdrawing off of Chantix but, in my opinion, it can come nowhere near the negatives of smoking or withdrawing off the *habit* of smoking.

And for the record, I did not go into this quit all gung ho and merry and *planning* to quit. My dr. just offered up the prescription when I was there about something else and I went ahead and filled it and figured I would at least try it, according to the directions. Because even though I had no direct plan to quit, I'm a smoker: of course I always want to quit. And I can say that from 11 days ago, with no specific plan to quit anytime soon, to 10 days ago starting my first pill, to 3 days ago having my last cigarette... I'm just stunned.
tony
Willow Grove, PA Reply »
|Flag |#38 Feb 8, 2007
Hi all!.

Chantix is the best quit aid I've ever had. I've created a forum to share our thoughts as well at http://waytoquit.blogspot.com/

please vist and post as I'd love to hear others experiences.

Thanks,
Tony
Carrie
Demorest, GA Reply »
|Flag |#39 Feb 10, 2007
Cathy Ottawa Canada wrote:
I'm thinking of trying Chantix to stop smoking. I did try Zyban but ended up having a major panic attack as a side effect (thought I was having a heart attack!). Has anyone experienced any increased anxiety from taking Chantix?
Cathy

Actually I have experienced quite the opposite. First Iâ€™m on my 5th week of Chantix and my 3rd week on being a non-smoker. Also I have a mild anxiety disorder. Iâ€™ve never taken any meds for my anxiety because normally I am able to handle the 3 to 4 minor anxiety attacks I have daily.
However, anxiety was one of the main concerns I had when I went to see my Dr. about Chantix. See, the last several times I tried quitting (using the patch) I would have full blown panic attacks several times a day. In the end I would give up because between the withdrawal and the panic attacks I would opt for a nicotine addiction every time. My doctor guessed that the reason for the panic attacks was because nicotine is a stimulant and with the patch I was getting a steady dose 24 hours a day as opposed to smoking which was only at certain times through out the day.
Let me tell youâ€¦. Not only have I not had any panic attacks while taking Chantix, my anxiety attacks have gone from 3 to 4 a day to 3 to 4 a week. I donâ€™t know why they have reduced. Maybe my anxiety is linked to the nicotine, maybe itâ€™s part of the mellowing effect the Chanix has, I donâ€™t know. All I can tell you is do not let your fear of anxiety deter you from this medication. Talk to your Dr about it, and tell him what youâ€™ve experienced in the past and let him judge it. Since these Drâ€™s they know a little about this stuff ya know ;^)
Also, just an FYI I took Welbutrin about a year ago to try and quit and had a horrible panic attack that was so bad I will never touch the stuff again. Iâ€™m not sure what triggered it with that med, and I never discussed it with my Dr. I just know that Welbutrin/Zyban is NOT for me.

Good Luck!!!
jtown
Monmouth Beach, NJ Reply »
|Flag |#40 Feb 14, 2007
I just started taking it, but my sister is on it and she also complained of being tired, and sometimes extra thirsty. I think to compensate for being tired, drink LOTs of liquids,good liquids that are good for you such as vitamin water, regular water, juice, ect. keeping your body hydrated keeps you going, even more so then coffee. I'm looking forward to feeling the effects of chantix in a few days. Hopefully I can quit this nasty habit.

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